Glucose metabolism and its role in the maturation and migration of human CD1c+ dendritic cells following exposure to BCG

IntroductionTuberculosis (TB) still kills over 1 million people annually.The only approved vaccine, BCG, prevents disseminated disease in children but shows low efficacy at preventing pulmonary TB.Myeloid dendritic cells (mDCs) are promising targets for vaccines and immunotherapies to combat infectious diseases due to their essential role in linkin

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Esters of quinoxaline-7-carboxylate-1,4-di-N-oxide as Trichomonas vaginalis triosephosphate isomerase inhibitors

Trichomoniasis is a public health problem worldwide.Trichomoniasis treatment consists of the use of nitroimidazole derivatives; however, therapeutic ineffectiveness occurs in 5 to 20 % of the cases.Therefore, it is Strap-ons essential to propose new pharmacological agents against this disease.In this work, esters of quinoxaline-7-carboxylate-1,4-di

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A pivotal role for ocean eddies in the distribution of microbial communities across the Antarctic Circumpolar Current.

Mesoscale variability and associated eddy fluxes play crucial roles in ocean circulation dynamics and the ecology of the upper ocean.In doing so, these features are biologically important, providing a mechanism for the mixing and exchange of nutrients and biota within the ocean.Transient mesoscale eddies in the Southern Ocean are known to relocate

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Patterns and Factors Influencing Parrot (Order: Psittaciformes) Success in Establishing Thriving Naturalized Populations within the Contiguous United States

Parrots (Order: Psittaciformes) represent one of the most striking and ecomorphologically diverse Watering Can avian clades, spanning more than two orders of magnitude in body size with populations occupying six continents.The worldwide diaspora of parrots is largely due to the pet trade, driven by human desire for bright, colorful, and intelligent

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